中国化妆品科学杂志

C14-16 烯烃磺酸钠体系复配辅助表活对洗发水温和性的影响研究

Study on the Effects of Co-surfactants on Mildness of Shampoo in Sodium C14-16 Olefin Sulfonate Systems

朱雅婷;林凤英;刘思欣;亓丰伟;杨洁 ZHU Yating;LIN Fengying;LIU Sixin;QI Fengwei;YANG Jie

以 C14-16 烯烃磺酸钠为主要表面活性剂，通过絮凝曲线、Zeta 电位、玉米醇溶蛋白溶解性、皮肤表面活性剂残留、红细胞溶血、鸡胚绒毛尿囊膜试验分析复配不同辅助表面活性剂对洗发水温和性的影响。结果表明，复配癸基葡糖苷和椰油酰谷氨酸二钠可以增加体系的温和性。复配月桂酰肌氨酸钠、椰油酰丙氨酸钠、月桂醇聚醚磺基琥珀酸酯二钠和甲基椰油酰基牛磺酸钠可使体系对玉米醇溶蛋白的溶解性增加，但其他指标结果显示月桂酰肌氨酸钠和椰油酰丙氨酸钠可以提升体系温和性，月桂醇聚醚磺基琥珀酸酯二钠和甲基椰油酰基牛磺酸钠不会降低体系的温和性。温和性表现较差的是硫酸盐阴离子表活，复配会导致体系温和性降低。

This study investigated the effects of various co-surfactants on the mildness of a shampoo system primarily composed of sodium C14-16 olefin sulfonate. The evaluation was conducted through flocculation curves, zeta potential measurements, zein solubility tests, skin surfactant residue analysis, hemolysis assays, and chorioallantoic membrane (HET-CAM) test. Results demonstrated that the incorporation of alkyl glycoside and disodium cocoyl glutamate significantly enhanced both the mildness of the formulation. While sodium lauroyl sarcosinate, sodium cocoyl alaninate, disodium laureth sulfosuccinate, and sodiummethyl cocoyl taurate improved zein protein solubility, further analysis revealed that sodium lauroyl sarcosinate and sodium cocoyl alaninate contributed to improved mildness, whereas disodium laureth sulfosuccinate and sodium methyl cocoyl taurate exhibited neutral effects on mildness. In contrast, sulfate-based anionic surfactants adversely affected mildness, leading to a deterioration in overall formulation tolerance.

膏霜中 α 凝胶结构形成的影响因素研究

Study on factors influencing the formation of α-gel structure in cream

苏晋峰 ;许彦婷;曾兰兰 SU Jinfeng ;XU Yanting;ZENG Lanlan

以甘油硬脂酸酯 SE 和柠檬酸硬脂酸甘油酯为主乳化剂构建不同的配方体系，采用慢速降温和快速降温两种配制工艺，制得含有 α 凝胶结构的膏霜样品。利用偏光显微镜（PLM）、小角和广角 X 射线衍射仪（SWAXS）观测膏霜中凝胶结构，结合差示扫描量热法（DSC）分析凝胶结构强度，研究乳化剂组合、生产工艺和储存方式对 α 凝胶结构形成及稳定性的影响。研究发现：甘油硬脂酸酯SE乳化体系、慢速降温工艺以及低温储存有利于膏霜的 α 凝胶结构的稳定。

Cream samples containing an alpha gel (α-gel) structure were formulated using two emulsifier systems—glyceryl stearate SE and glyceryl stearate citrate—along with two cooling methods: slow cooling and rapid cooling. The gel structure within the creams was characterized by polarizing microscopy (PLM) and X-ray diffraction (SWAXS), while its structural strength was assessed using differential scanning calorimetry (DSC), which together enabled a comprehensive evaluation of the effects of emulsification system of glycerol stearate SE, slow cooling process and low temperature storage are beneficial to the stability of the α-gel structure of the cream.

茶麸皂苷氨基酸洗发水的配方设计研究

Research on formula design of tea bran saponin amino acid shampoo

李达焱 ;石亚宁;王昕琦;虞点;李晓航;汪源浩 ;谭凤芝 LI Dayan;SHI Yaning;WANG Xiqi;YU Dian;LI Xiaohang; WANG Yuanhao;TAN Fengzhi

针对合成洗发水过度清洁、刺激性强及天然洗发水清洁力不足、泡沫量少等问题，设计开发了一款以茶麸皂苷与氨基酸表面活性剂复配为核心的绿色洗发水。通过单因素实验确定了最佳的配方比例：月桂酰胶原氨基酸钠（SLCMAA）添加量 20%、甜菜碱添加量 8%、茶麸、侧柏叶、何首乌的添加量分别为 7%、2%、2%。在此配方比例下，洗发水的泡沫高度最大、清洁力最强，感官评价 88 分，pH 值稳定在 5.5-6.0。另外，通过采用乙基己基甘油和苯氧乙醇复配实现洗发水的防腐，使产品保质期大于 90 天。该洗发水配方实现了清洁 - 养发 - 环保三重功效于一体，为天然洗护产品开发提供了新思路。

In order to solve the problems of over cleaning, strong irritation of synthetic shampoo, insufficient cleaning power of natural shampoo and less foam, a green shampoo based on the combination of tea bran saponin and amino acid surfactant was designed and developed. The optimal formula ratio was determined through single factor experiments: the addition of sodium lauroyl collagen amino acid (SLCMAA) was 20%, betaine was 8%, and the addition of tea bran, Platycodon grandiflorus leaves, and Polygonum multiflorum were 7%, 2%, and 2%, respectively. Under this formula proportion, the foam of shampoo has the highest height and the strongest cleaning power. The sensory evaluation is 88 points, and the pH is stable at 5.5-6.0. In addition, by using a combination of ethylhexylglycerin and phenoxyethanol to prevent corrosion in shampoo, the product's shelf life is extended beyond 90 days. This shampoo formula achieves the triple effects of cleaning, hair care, and environmental protection, providing new ideas for the development of natural hair care products.

茶麸皂苷氨基酸洗发水的配方设计研究

Research on formula design of tea bran saponin amino acid shampoo

李达焱 ;石亚宁;王昕琦;虞点;李晓航;汪源浩 ;谭凤芝 LI Dayan;SHI Yaning;WANG Xiqi;YU Dian;LI Xiaohang; WANG Yuanhao;TAN Fengzhi

针对合成洗发水过度清洁、刺激性强及天然洗发水清洁力不足、泡沫量少等问题，设计开发了一款以茶麸皂苷与氨基酸表面活性剂复配为核心的绿色洗发水。通过单因素实验确定了最佳的配方比例：月桂酰胶原氨基酸钠（SLCMAA）添加量 20%、甜菜碱添加量 8%、茶麸、侧柏叶、何首乌的添加量分别为 7%、2%、2%。在此配方比例下，洗发水的泡沫高度最大、清洁力最强，感官评价 88 分，pH 值稳定在 5.5-6.0。另外，通过采用乙基己基甘油和苯氧乙醇复配实现洗发水的防腐，使产品保质期大于 90 天。该洗发水配方实现了清洁 - 养发 - 环保三重功效于一体，为天然洗护产品开发提供了新思路。

In order to solve the problems of over cleaning, strong irritation of synthetic shampoo, insufficient cleaning power of natural shampoo and less foam, a green shampoo based on the combination of tea bran saponin and amino acid surfactant was designed and developed. The optimal formula ratio was determined through single factor experiments: the addition of sodium lauroyl collagen amino acid (SLCMAA) was 20%, betaine was 8%, and the addition of tea bran, Platycodon grandiflorus leaves, and Polygonum multiflorum were 7%, 2%, and 2%, respectively. Under this formula proportion, the foam of shampoo has the highest height and the strongest cleaning power. The sensory evaluation is 88 points, and the pH is stable at 5.5-6.0. In addition, by using a combination of ethylhexylglycerin and phenoxyethanol to prevent corrosion in shampoo, the product's shelf life is extended beyond 90 days. This shampoo formula achieves the triple effects of cleaning, hair care, and environmental protection, providing new ideas for the development of natural hair care products.

C14-16 烯烃磺酸钠体系复配辅助表活对洗发水温和性的影响研究

Study on the Effects of Co-surfactants on Mildness of Shampoo in Sodium C14-16 Olefin Sulfonate Systems

朱雅婷;林凤英;刘思欣;亓丰伟;杨洁 ZHU Yating;LIN Fengying;LIU Sixin;QI Fengwei;YANG Jie

以 C14-16 烯烃磺酸钠为主要表面活性剂，通过絮凝曲线、Zeta 电位、玉米醇溶蛋白溶解性、皮肤表面活性剂残留、红细胞溶血、鸡胚绒毛尿囊膜试验分析复配不同辅助表面活性剂对洗发水温和性的影响。结果表明，复配癸基葡糖苷和椰油酰谷氨酸二钠可以增加体系的温和性。复配月桂酰肌氨酸钠、椰油酰丙氨酸钠、月桂醇聚醚磺基琥珀酸酯二钠和甲基椰油酰基牛磺酸钠可使体系对玉米醇溶蛋白的溶解性增加，但其他指标结果显示月桂酰肌氨酸钠和椰油酰丙氨酸钠可以提升体系温和性，月桂醇聚醚磺基琥珀酸酯二钠和甲基椰油酰基牛磺酸钠不会降低体系的温和性。温和性表现较差的是硫酸盐阴离子表活，复配会导致体系温和性降低。

This study investigated the effects of various co-surfactants on the mildness of a shampoo system primarily composed of sodium C14-16 olefin sulfonate. The evaluation was conducted through flocculation curves, zeta potential measurements, zein solubility tests, skin surfactant residue analysis, hemolysis assays, and chorioallantoic membrane (HET-CAM) test. Results demonstrated that the incorporation of alkyl glycoside and disodium cocoyl glutamate significantly enhanced both the mildness of the formulation. While sodium lauroyl sarcosinate, sodium cocoyl alaninate, disodium laureth sulfosuccinate, and sodiummethyl cocoyl taurate improved zein protein solubility, further analysis revealed that sodium lauroyl sarcosinate and sodium cocoyl alaninate contributed to improved mildness, whereas disodium laureth sulfosuccinate and sodium methyl cocoyl taurate exhibited neutral effects on mildness. In contrast, sulfate-based anionic surfactants adversely affected mildness, leading to a deterioration in overall formulation tolerance.

膏霜中 α 凝胶结构形成的影响因素研究

Study on factors influencing the formation of α-gel structure in cream

苏晋峰 ;许彦婷;曾兰兰 SU Jinfeng ;XU Yanting;ZENG Lanlan

以甘油硬脂酸酯 SE 和柠檬酸硬脂酸甘油酯为主乳化剂构建不同的配方体系，采用慢速降温和快速降温两种配制工艺，制得含有 α 凝胶结构的膏霜样品。利用偏光显微镜（PLM）、小角和广角 X 射线衍射仪（SWAXS）观测膏霜中凝胶结构，结合差示扫描量热法（DSC）分析凝胶结构强度，研究乳化剂组合、生产工艺和储存方式对 α 凝胶结构形成及稳定性的影响。研究发现：甘油硬脂酸酯SE乳化体系、慢速降温工艺以及低温储存有利于膏霜的 α 凝胶结构的稳定。

Cream samples containing an alpha gel (α-gel) structure were formulated using two emulsifier systems—glyceryl stearate SE and glyceryl stearate citrate—along with two cooling methods: slow cooling and rapid cooling. The gel structure within the creams was characterized by polarizing microscopy (PLM) and X-ray diffraction (SWAXS), while its structural strength was assessed using differential scanning calorimetry (DSC), which together enabled a comprehensive evaluation of the effects of emulsification system of glycerol stearate SE, slow cooling process and low temperature storage are beneficial to the stability of the α-gel structure of the cream.

第三届中国化妆品产学研协同创新论坛在沪召开：共探行业创新与高质量发展之路

The Third China Cosmetics Industry-University-Research Collaborative Innovation Forum was held in Shanghai, exploring pathways for industry innovation and high-quality development

陈璇 CHEN Xuan

第三届中国化妆品产学研协同创新论坛在第 29 届 CBE 中国美容博览会上成功举办。本届论坛以“双创新驱赋能产业，四链协同贯通发展”为主题，汇聚了顶尖专家学者、知名企业领袖及行业精英，共同探讨化妆品领域的技术创新、产学研协同与产业升级路径，为推动中国化妆品行业高质量发展注入强劲动力。

The 3rd China Cosmetics Industry-Academia-Research Collaborative Innovation Forum was successfully held at the 29th CBE China Beauty Expo. With the theme of "Dual Innovation Driving Industrial Empowerment, Four Chains Synergizing Development," the forum brought together top experts, renowned corporate leaders, and industry elites to explore technological innovation, industry-academia-research collaboration, and industrial upgrading pathways in the cosmetics sector, injecting strong momentum to propel the high-quality development of China's cosmetics industry.

《化妆品原料使用目的技术指南（征求意见稿）》 解读及思考

Interpretation and Reflection on the Technical Guidelines for the Use of Cosmetics Raw Materials (Draft for Comments)

钟盈盈;桑祯玉;陶沁倩;严二平 ZHONG Yingying;SANG Zhenyu;TAO Qinqian;YAN Erping

2025 年 10 月，中国食品药品检定研究院发布了《化妆品原料使用目的技术指南（征 求意见稿）》（以下简称《指南征求意见稿》），旨在规范化妆品及其新原料注册备案时原料使用目的的填报。本文通过对比分析现有规范性文件，表明《指南征求意见稿》通过规范化 70 种原料使用目的，系统性地填补了原料填报环节的技术规范空白，并对关键功效宣称相关的原料目的进行了清晰界定与科学收窄，这要求企业对于在研产品及存量产品均做出积极应对。企业需主动适应这一监管深化趋势，通过提升内部科学评估能力与完善合规流程，以实现可持续发展。

In October 2025, the China National Institute for Food and Drug Control released the "Technical Guidelines for the Purpose of Use of Cosmetics Raw Materials (Draft for Comments)" (hereinafter referred to as the "Draft Guidelines for Comments"), aiming to standardize the reporting of the purpose of use of raw materials in the registration and filing of cosmetics and their new raw materials. This article compares and analyzes existing normative documents, indicating that the "Draft Guidelines for Soliciting Opinions" systematically fills the technical specification gap in the raw material reporting process by standardizing the use of 70 types of raw materials, and clearly defines and scientifically narrows the raw material purposes related to key efficacy claims. This requires enterprises to actively respond to both research and existing products. Enterprises need to proactively adapt to this trend of deepening regulation, by enhancing their internal scientific evaluation capabilities and improving compliance processes, in order to achieve sustainable development.

解锁胶原蛋白肽的青春密码：结构特性、生物活性 及美妆应用

Unveiling the Youthful Secret of Collagen Peptides: Structural Characteristics, Biological Activities and Cosmetic Applications

曾俊雅 ，但晔，王俊杰，但俊，时炜，但卫华 ZENG Junya;DAN Ye;WANG Junjie;DAN Jun;SHI Wei;DAN Weihua

v> 本文系统综述了胶原蛋白肽在抗皮肤光老化中的应用及其作用机制。文章指出，胶原 蛋白肽通过促进胶原再生、抑制 MMPs 活性、抗氧化与抗炎等多重途径发挥功效，其活性高度依 赖于分子量、羟脯氨酸含量及特征氨基酸序列。针对当前应用中存在的“透皮 - 活性”矛盾，本 文总结了离子液体修饰、纳米载体等先进递送技术在提升透皮性与稳定性方面的进展，并强调了 其与抗氧化剂、透明质酸等活性成分复配的协同效应。最后，提出未来应致力于开发高效递送系统、 拓展可持续原料来源及构建科学评价体系，以推动胶原蛋白肽在化妆品领域中的更高效、科学化 应用。

This paper systematically reviews the application and mechanisms of collagen peptides in anti-photoaging. It highlights their multi-target efficacy, including promoting collagen synthesis, inhibiting MMP activity, and providing antioxidant and anti-inflammatory benefits, all highly dependent on molecular weight,hydroxyproline content, and specific amino acid sequences. To address the “transdermal-activity paradox,” advanced strategies such as ionic liquid modification and nanocarriers are summarized for enhancing skin penetration and stability. Synergistic effects achieved through combination with antioxidants or hyaluronic acid are also emphasized. Future efforts should focus on developing efficient delivery systems, sustainable sourcing, and scientific evaluation to advance the cosmetic applications of collagen peptides.

坛紫菜类菌孢素氨基酸（MAAs）储存条件初探及 在化妆品防晒体系复配稳定性研究

Preliminary Study on Storage Conditions of Mycosporin Amino Acids (MAAs) in Porphyra haitanensis and Its Compound Stability in Cosmetic Sunscreen System

赵永斌;李晓雅;车小梅;张艳;程凯欣;李伟 ZHAO Yongbin;LI Xiaoya;CHE Xiaomei;ZHANG Yan;CHENG Kaixin;LI Wei

以坛紫菜为原料，提取类菌孢素氨基酸（MAAs），通过高效液相色谱（HPLC）技术 鉴定其主要成分为 Shionrine 和 Porphyra-334, 经紫外光谱扫描显示两者最大吸收峰均在 334nm。系统探究了温度、pH、光照及储存时长对 MAAs 稳定性的影响，并进一步评估芦荟提取物、迷迭香提取物及绿茶多酚与 MAAs 的复配效果与加入蚕丝蛋白粉、珍珠粉对 MAAs 光稳定性的影响。结果表明：低温（-18℃）、中性条件（pH=6）及避光储存可明显抑制 MAAs 的降解（45℃下分解率 18% ; -18℃下 <1%）；复配体系中，芦荟提取物对 MAAs 的稳定性提升效果最佳（分解率仅 3.1%）；蚕丝蛋白粉珍珠粉混合物对维持 MAAs 的光稳定性有较好的效果。并对不同体系防晒效果进行评估为开发基于坛紫菜 MAAs 的天然生物防晒剂及其防晒成分复配体系提供了理论依据。

Mycosporine amino acids (MAAs) were extracted from Porphyra haitanensis. The main components were identified as Shionrine and Porphyra-334 by high performance liquid chromatography (HPLC), and the maximum absorption peaks of both were 334 nm. The effects of temperature, pH, light and storage time on the stability of MAAs were systematically investigated, and the effects of aloe vera extract, rosemary extract, green tea polyphenols and MAAs were further evaluated. The effects of silk protein powder and pearl powder on the photostability of MAAs were further evaluated. The results showed that: low temperature (-18 ℃), neutral conditions (pH = 6) and dark storage can significantly inhibit the degradation of MAAs (decomposition rate 18% at 45 ℃;-18 ℃ < 1%); in the compound system, aloe vera extract has the best effect on improving the stability of MAAs (decomposition rate is only 3.1%); silk protein powder and pearl powder mixture have a good effect on maintaining the photostability of MAAs.It also evaluates the sunscreen effects of different systems, providing a theoretical basis for the development of natural biological sunscreens based on MAAs from Porphyra haitanensis and their compound systems of sunscreen ingredients.

中药经典古方在功能性化妆品中的应用

Application of Classical Ancient Prescriptions of Traditional Chinese Medicine in Functional Cosmetics

张灵凤;陈刚;董迎旭;李宁 Zhang Lingfeng;Chen Gang;Dong Yingxu;Li Ning

随着科技进步及人们对皮肤健康的追求逐渐提升，一些来自于中药的提取物或功效成 分越来越多地应用到功能性化妆品中，然而许多具有潜在美容价值的古代中药方剂还未被开发。 文章综述了中药及复方在功能性化妆品中的应用，分析了中药经典名方在化妆品开发领域的应用 前景，探讨了网络药理学方法等技术手段对于开发中药经典名方化妆品的助力作用，为中药经典 名方功能性化妆品的研发提供了新思路。

With the advancement of science and technology and people's demand of skin health, Some extracts or efffcacy ingredients from traditional Chinese medicine (TCM) are increasingly used in functional cosmetics. However, many ancient TCM formulae with potential cosmetic value have not yet been developed. These ancient formulae follow the TCM theory of compounding, which reffects a greater advantage in terms of efffcacy. This paper summarizes the application of TCM and compound formulae in functional cosmetics, analyzes the application prospects of classical TCM formulae in the ffeld of cosmetic development, and discusses the role of network pharmacological method and other technical means for the development of classical TCM formulae in functional cosmetic products, which provides a new way of thinking for the research and development of functional cosmetics with classical TCM formulae. 

含泛醇的特护防晒霜在光子嫩肤（IPL）术后的多 维度功效评估：一项随机对照临床研究

Multidimensional Efficacy Evaluation of a Panthenol-Containing Sunscreen for Post-Intense Pulsed Light (IPL) Therapy: A Randomized Controlled Clinical Study

李蕊;李白玉;陈洋;张琪琳;赵纯玉;王文娜;朱再凌;何晓峰;周晓音;裘捷;易奕;牛悦青;HUGUET Claire;XIONG Wendy;郑一诫 LI Rui;LI Baiyu;CHEN Yang;ZHANG QilinZHAO Chunyu;WANG Wenna;ZHU Zailing;HE Lingfeng;ZHOU Xiaoyin;QIU Jie;YI Yi;NIU Yueqing;HUGUET Claire;XIONG Wendy;ZHENG Yijie

IPL 术后皮肤屏障脆弱、对紫外线呈现高敏感性，目前较少有解决方案能够同时针对 IPL 后的屏障修护和紫外线防护问题。本研究旨在评估一种含泛醇的特护防晒霜应用于 IPL 术后皮肤的多维度功效。本研究招募 89 名受试者（试验组 44 人，对照组 45 人），在 IPL 术后开展28 天使用周期，通过 VISIA 红区分析、角质层水分含量、经皮水分流失、皮肤光泽度等仪器参数结合医生临床评估多个维度评估术后功效。结果表明，IPL 术后使用 28 天，其中角质层水分含量试验组增幅达 25.19%，较对照组的 2.70% 高出 22.49%；经皮水分流失率（TEWL）试验组降低8.50%，较对照组的 2.44% 低 6.06%；皮肤红区 a * 值试验组改善 10.60%，较对照组的 4.48% 高出 6.12%；皮肤光泽度试验组提升 20.37%，较对照组的 3.72% 高出 16.65%, 且各个指标均显著优于对照组。更进一步在医生临床评估中，试验组在各个医生评估指标中均显著优于对照组。总的来说，对于皮肤科医生和消费者，未来一种含泛醇的特护防晒霜是 IPL 术后修护和紫外线防护一体化解决方案的潜在选择。

Post-IPL skin shows fragile barrier and high sensitivity to ultraviolet radiation, yet few existing solutions can simultaneously address both barrier repair and UV protection after IPL treatment. This study evaluated the multidimensional efficacy of a panthenol-containing specialized sunscreen for post-IPL skin. We enrolled 89 subjects (44 in the test group and 45 for controls) for a 28-day study after IPL treatment. Efficacy was assessed through multiple dimensions including VISIA erythema analysis, stratum corneum hydration content, transepidermal water loss (TEWL), skin glossiness measurements, along with dermatologist clinical evaluations. Results showed that after 28 days of use, the test group demonstrated significantly better improvements than controls in all instrumental parameters: skin redness (a* value), stratum corneum hydration, TEWL, and skin glossiness (all p<0.05). Furthermore, in dermatologist assessments, the test group outperformed controls across all evaluation indicators. In conclusion, a panthenol-enriched specialized sunscreen could serve as a potential integrated solution combining post-IPL repair with UV protection for both dermatologists and consumers.

皮肤抗衰老策略最新进展

Recent Advances in Skin Anti-Aging Strategies

邬故渊;王伟 Wu Guyuan;Wang Wei

在当前社会老龄化趋势日益显著的背景下，人们越来越关注自身健康与外貌的维护， 对皮肤老化的研究日益受到关注。文章在阐述皮肤基本构造与生理功能的基础上，系统性介绍皮 肤衰老的核心学说，包括自由基与氧化应激、光老化、非酶糖基化、端粒与复制性衰老与炎症学说。 在皮肤衰老过程中，这些学说相互交织、共同发挥作用。此外，抗衰老领域也迎来了诸多最新研 究进展，其聚焦于抗氧化剂、糖基化终产物抑制剂、DNA 修复酶以及天然抗炎成分等，这些策略 与皮肤衰老核心学说紧密相关，通过多维度干预从而减缓并逆转皮肤衰老过程。文章旨在为皮肤 抗衰老研究提供理论基础和新的研究策略，以期推动该领域研究的深入发展与创新突破。

Against the background of the current trend of aging society, people are more and more concerned about the maintenance of their own health and appearance, and the study of skin aging has received increasing attention. Based on the basic structure and physiological functions of the skin, the article systematically introduces the core doctrines of skin aging, including free radicals and oxidative stress, photoaging, nonenzymatic glycosylation, telomere and replicative aging, and inffammation. These doctrines are intertwined and work together in the skin aging process. In addition, the ffeld of anti-aging has seen many recent advances in research focusing on antioxidants, inhibitors of glycosylation end products, DNA repair enzymes, and natural anti-inffammatory ingredients, which are strategies that are closely related to the core doctrines of skin aging, and that slow down and reverse the process of skin aging through multidimensional interventions. The aim of this article is to provide a theoretical basis and new research strategies for skin anti-aging research, and to promote the further development and innovation in this field.